Where Centretown, the Glebe, Little Italy, and Chinatown meet, 481 Cambridge Street South places you in the middle of Ottawa's most vibrant neighborhoods, with cafés, shops, transit, and green spaces all within easy reach. Set on a rare 29 x 150 ft lot with R4 zoning, this detached century home blends character with opportunity. Inside, you'll find original architectural details, including high baseboards, that speak to the home's history, while hardwood flooring carries through the main level's formal living and dining rooms, spaces made for both everyday living and hosting. At the back of the home, the updated kitchen features a gas stove, combining function with a chef friendly touch, and flows seamlessly into a versatile den/office, ideal for working from home or creating a quiet retreat, with direct access to the backyard. Step outside to discover the full depth of the lot, an extra deep yard with a deck, storage shed, and endless potential for outdoor living, gardening, or future development. Upstairs offers 3 bedrooms and a full bathroom, while a convenient main floor powder room adds functionality. The unfinished basement includes laundry and generous storage space, and a private long driveway ensures practical parking in this central location. A rare opportunity to own a character filled home on an oversized lot in one of Ottawa's most connected and sought after locations. Some photos have been virtually staged.